Mortal Kombat 1 is largely same as OTL but with Jean Claude Van Damme as Johnny Cage.
Mortal Kombat 2 has Sonya(played by Kathy Long) return but not Kano, who is replaced by a playable Kintaro, who is a Stop Motion Tiger Man. This removes Mileena and Reptile from the game.
Mortal Kombat 3 has a dispute over royalties settled, as a result many of the original actors from the first two games reprise their roles. Due to the changes above, Mileena and Reptile debut in this game, replacing Sektor and Sheeva.
Mortal Kombat: Mythologies Sub Zero does not exist ITTL.
Mortal Kombat 4 has a few different characters, Kano replaces Jarek(Jarek's OTL ending is Jaxs ending instead, while Sonya's is similar but she survives), Bo Rai Cho replaces Kai(and lacks the fart and vomit jokes ITTL, but is instead a drunken master type), Mileena instead of Meat, Shao Kahn, and Jade. This game is Quan Chi's debut due to MK Mythologies and the Mortal Kombat Cartoon not existing. As a result it is this game that reveals Quan Chi's role in framing Sub Zero for the murder of Scorpion's family and clan, which Scorpion finds out after defeating Sub Zero and then goes to confront Quan Chi in the final battle.
While the Mortal Kombat series is doing a bit better than OTL, Mortal Kombat: Deadly Alliance includes Liu Kang, Shao Khan, Goro, Kabal and Motaro, who replace Drahmin, Hsu Hao, Mokap, and Mavado. Several in cutscene only events are shown, including the death of Liu Kang and Shao Khan in the game's story mode.
For Mortal Kombat: Deception no Console exclusive characters exist. As a result Shao Khan, Goro, Blaze, Frost, Jax and Kitana are playable, replacing Ashrah,Dairou, Darrius, Hotaru, Kira and Kobra.
Mortal Kombat: Warriors of the Realms was a Beat em up style game going through the first trilogy. Several characters were playable and not just Liu Kang and Kung Lao.
Mortal Kombat Armaggedon was released with every playable character in the franchise, including Chameleon(male and female).
Mortal Kombat vs Street Fighter, replacing Mortal Kombat vs DC Universe. This game is animated with traditional looking sprites and does include fatalities, though by the Mortal Kombat characters, albeit somewhat censored(the screen cuts to silhouettes of the characters as fatalities are performed). This game saved Midway from bankruptcy.
Mortal Kombat: Resurrection is a Kontinuation of the series after Armaggeddon rather than a reboot, showing the survivors of the final battle as they wage a final war to destroy their enemies. Character chapters are instead split and allow the player to choose who to play as. If there are multiple opponents, the character the player did not choose will then be played as in that fight as well. The roster on Playstation 3 includes Kratos and Sweet Tooth while the Xbox 360 includes Master Chief and Marcus Phoenix. The DLC pack included all four of these characters made playable to everyone at the price of only two characters(since most people who owned one of the consoles would already have two of them). Freddy Krueger therefore does not appear, and the game's plot means neither does Cyber Sub Zero.
Mortal Kombat X follows a new generation of Fighters, years after the conclusion of the last game. Kiefer Sutherland voices Erron Black. New characters include Cassie Cage, D'Vorah, Erron Black, Jacqui Briggs, Kotal Khan, Kun Jin and Takeda with Kotal Khan as the antagonist. The plot of the game is therefore more streamlined without incorporating the Shinnok plot. Kombat Pack 1 is all the guest stars in Jason Voorhees, Freddy Krueger, The Xenomorph and the Predator. Kombat Pack 2 is Tanya, Tremor, Bo Rai Cho and Triborg.
Mortal Kombat II has Kronika as an antagonist but lacks the time travel plot, but is able to create clones of warriors from certain points in their lives. D'Vorah, having been killed in the previous game, does not return, and there are no new characters. The three new characters of Centrion, Geras and Collector are replaced by Sindel, Nightwolf and Shang Tsung. Sindel's portrayal is much more positive and in line with Sheeva or Kotal Khan's portrayal as they are the restored kind Queen of Edenia along with her daughter Kitana and husband Jareth(possessing the body of Ermac as Jareth was one of the souls used to create him). The 3 Kombat Packs are all guest characters and themed. There is the Comic Pack(Joker and Spawn with the ITTL only inclusion of Deadpool), Action Pack which includes Rambo, Robocop and the Terminator(voiced by Arnold Shwarzenagger ITTL), The Horror Pack(Which brings back Freddy, Jason and throws in Ash Williams from Evil Dead). A unnamed Fourth Pack added three extra characters representing each pack, two of which were returnees in Hellboy, the Predator and Pennywise, the Dancing Clown.